Sirisak

Chanprasert

MD

Biography

Dr. Chanprasert graduated from Faculty of Medicine, Siriraj Hospital, Mahidol Univeristy, Bangkok, Thailand. He did internal medicine residency training at Bassett Medical Center, Cooperstown, NY. He finished medical genetics and medical biochemical genetics residency and fellowship training at Baylor College of Medicine, Houston, TX. He is one of a few physicians who board certified in internal medicine, medical genetics, and medical biochemical genetics. In addition, he did mitochondrial medicine research fellowship at Seattle Children’s Research Institute and Seattle Children’s Hospital for 1 year at the center of developmental therapeutics. After completed training, he joined Division of Medical Genetics, Department of Medicine at University of Washington Medical School.

Education & Training

Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand (1999-2005)

Resident, Internal Medicine, Bassett Medical Center, Cooperstown, New York (2009-2012)

Resident, Medical Genetics, Baylor College of Medicine, Houston, Texas (2012-2014)

Fellowship, Medical Biochemical Genetics, Baylor College of Medicine, Houston, Texas (2014-2015)

Fellowship, Academic/Research Genetics Fellowship, University of Washington, Seattle, WA (2015-2016)

Research Interests

Dr. Chanprasert is interested in doing clinical research to characterize adult-onset metabolic conditions to lead to the way of effective treatment. In addition, he is interested in therapeutic trials of mitochondrial diseases.

Clinical Interests

Dr. Chanprasert is interested in adult-onset metabolic and mitochondrial diseases which were once thought to be diseases of children. He is also interested in establishing transitional care of patients with genetic conditions who are growing into adulthood.

publications

• Molecular and clinical characterization of the myopathic form of mitochondrial DNA depletion syndrome caused by mutation in the thymidine kinase (TK2) gene.  Chanprasert S, Wang J, Weng SW, Enns GM, Boue DR, Wong BL, Mendell JR, Perry DA, Sahenk Z, Craigen WJ, Alcala FJ, Pascual JM, Melancon S, Zhang VW, Scaglia F, Wong LJ. Mol Genet Metab. 2013 Sep-Oct; 110(1-2):153-61 [original work]
• Mitochondrial: role of citrulline and arginine supplementation in MELAS syndrome. El-Hattab AW, Emrick LT, Chanprasert S, Craigen WJ, Scaglia F. Int J Biochem Cell Biol. 2014 Mar; 48:85-91 [review]
• Heterozygous deletion of exons 18 and 19 of IGF1R in an individual with short stature. Chanprasert S, Smith JL, Hixson P, Patel A, Lalani SR. Clin Dysmorphol. 2014 Mar 3 [original work]
• Glucose metabolism derangements in adults with the MELAS m.3243 A>G mutation. El-Hattab AW, Emrick LT, Hsu JW, Chanprasert S, Jahoor F, Scaglia F, Craigen WJ.Mitochondrion. 2014 Jul 30. Pii S1567-7249(14)00099-3 [original work]
• Adult liver disorders caused by inborn errors of metabolism: review and update. Chanprasert S. Scaglia F. Mol Genet Metab. 2014 Nov 5. Pii S1096-7192(14)00337-0 [original work]
• Impaired nitric oxide production in children with MELAS syndrome and the effect of arginine and citrulline supplementation. El-Hattab AW, Emrick LT, Hsu JW, Chanprasert S, Almannai M, Craigen W, Jahoor F, Scaglia F. Mol Genet Metab. 2016 April; 117(4):407-12 [review]
• WRN Mutation Update: Mutation Spectrum, Patient Registries, and Translational prospects. Yokote K, Chanprasert S, Lee L, Eirich K, Takemoto M, Watanabe A, Koizumi N, Lessel D, Mori T, Hisama FM, Ladd PD, Angle B, Baris H, Cefle K, Palanduz S, Ozturk S, Chateau A, Deguchi K, Easwar TK, Federico A, Fox A, Grebe TA, Hay B, Nampoothiri S, Seiter K, Streeten E, Piña-Aguilar RE, Poke G, Poot M, Posmyk R, Martin GM, Kubisch C, Schindler D, Oshima J. Hum Mutat. 2017 Jan; 38(1): 7-15 [original work]